NFL · Week 4 · Sunday, October 4, 2026
New England Patriots vs Buffalo Bills — Live Score & Odds
● LiveNew England Patriots 21, Buffalo Bills 17
EdgeBets Model Projection
Projected margin
Buffalo Bills by 4.1
Market spread at publication
-7.0
We projected Buffalo Bills by 4.1. They lost by 4.
We called Buffalo Bills on the moneyline. That call has not been graded yet.
We called New England Patriots on the spread at +7.0. That call has not been graded yet.
Our ratings lean Buffalo Bills.
Our model's projection, shown for informational purposes — not betting advice, and not a claim to beat the market.
Pre-Game Market (for reference)
as of Oct 4, 12:00 PM ETTotal
49.5
median of 6 books
Moneyline: New England Patriots +280 (BetMGM) · Buffalo Bills -162 (FanDuel)
Last price captured Oct 4, 12:00 PM ET.
Every sportsbook: spread, total and moneyline
| Sportsbook | Buffalo Bills | New England Patriots | Spread | Total |
|---|---|---|---|---|
| bet365🌎 | -325 | +260 | -6.5(-120) | 49.5(o-109 / u-112) |
| BetMGM🇺🇸 | -350 | +280Best | -6.5(-122) | 49.5(o-110 / u-110) |
| BetRivers🇺🇸 | -325 | +260 | -7(-105) | 49.5(o-108 / u-110) |
| Caesars🇺🇸 | -335 | +260 | -7(-104) | 49.5(o-113 / u-108) |
| DraftKings🇺🇸 | -325 | +260 | -7(-108) | 49.5(o-108 / u-112) |
| FanDuel🇺🇸 | -162Best | +136 | -3(-110) | 49.5(o-110 / u-110) |
6 sportsbooks shown. Prices are the latest captured snapshot for each book, not a live feed.
New England Patriots vs Buffalo Bills: the numbers on this game
New England Patriots play Buffalo Bills on Sunday, October 4, 2026, Week 4 of the 2026 NFL season, kicking off at 13:00 ET.
Across 6 books the point spread runs -7 to -3 and the Buffalo Bills moneyline -350 to -162. All 6 books post the same game total (49.5). Worth a minute of comparing before you take a price.
Odds are collected from public sportsbook feeds on a schedule and carry the timestamp they were captured — lines move, so confirm the number at the sportsbook before betting. EdgeBets does not take bets and does not claim to beat the closing line. 19+. Please bet responsibly.
Other NFL games on Sunday, October 4, 2026
- Indianapolis Colts vs Washington Commanders · 09:30 ET
- Tennessee Titans vs Baltimore Ravens · 13:00 ET
- New York Jets vs Chicago Bears · 13:00 ET
- Jacksonville Jaguars vs Cincinnati Bengals · 13:00 ET
- Dallas Cowboys vs Houston Texans · 13:00 ET
- Arizona Cardinals vs New York Giants · 13:00 ET
- Los Angeles Rams vs Philadelphia Eagles · 13:00 ET
- Green Bay Packers vs Tampa Bay Buccaneers · 13:00 ET
- Miami Dolphins vs Minnesota Vikings · 16:05 ET
- Kansas City Chiefs vs Las Vegas Raiders · 16:25 ET
- Denver Broncos vs San Francisco 49ers · 16:25 ET
- Los Angeles Chargers vs Seattle Seahawks · 16:25 ET