MLB · Friday, May 22, 2026
St. Louis Cardinals vs Cincinnati Reds — Prediction, Projected Score & Odds
St. Louis Cardinals schedule & results·Cincinnati Reds schedule & results
First pitch 18:40 (local)
EdgeBets Model Projection
St. Louis Cardinals
4.2
Projected Total
9.2
Cincinnati Reds
5.0
Our model's simulation, shown for informational purposes — not betting advice, and not a claim to beat the market.
Moneyline Odds by Sportsbook
as of May 22, 7:00 PM ET| Book | St. Louis Cardinals | Cincinnati Reds |
|---|---|---|
| bet365 | -110 | -110 |
| betmgm | -100 | -118 |
| betrivers | +105 | -125 |
| draftkings | +101 | -122 |
| fanduel | -105 | -116 |
| pinnacle | +108 | -117 |
Best available price (last update — verify before betting): St. Louis Cardinals +108 at Pinnacle. Cincinnati Reds -110 at bet365.
Odds last updated May 22, 7:00 PM ET — lines move; confirm the current price at the sportsbook before betting.
St. Louis Cardinals vs Cincinnati Reds: the matchup & where to bet it
EdgeBets' model projects St. Louis Cardinals vs Cincinnati Reds at about 4.2–5.0, a total near 9.2 runs. The St. Louis Cardinals moneyline ranges from -110 to +108 across 6 books, a 218-point spread — line-shopping meaningfully changes the payout here. Right now the best prices are +108 (pinnacle) on St. Louis Cardinals and -110 (bet365) on Cincinnati Reds.
EdgeBets does not claim to beat the closing line or guarantee outcomes. Projections are informational. 19+. Please bet responsibly.