MLB · Wednesday, April 22, 2026

Houston Astros vs Cleveland Guardians — Result, Odds & Recap

Houston Astros schedule & results·Cleveland Guardians schedule & results

Final: Houston Astros 2, Cleveland Guardians 0

Closing Moneyline Odds

as of Apr 22, 7:00 PM ET
BookHouston AstrosCleveland Guardians
bet365+118-140
betmgm+136-162
betrivers+135-160
caesars+135-167
draftkings+139-168
espnbet+108-134
fanduel+108-126
pinnacle+144-157

Houston Astros vs Cleveland Guardians: recap & odds

Houston Astros beat Cleveland Guardians 2–0 on Wednesday, April 22, 2026. Closing moneyline prices ranged across 8 sportsbooks: Houston Astros from +108 to +144.

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