MLB · Tuesday, April 21, 2026
Houston Astros vs Cleveland Guardians — Result, Odds & Recap
Houston Astros schedule & results·Cleveland Guardians schedule & results
Final: Houston Astros 5, Cleveland Guardians 8
Closing Moneyline Odds
as of Apr 21, 7:00 PM ET| Book | Houston Astros | Cleveland Guardians |
|---|---|---|
| bet365 | +130 | -155 |
| betmgm | +130 | -154 |
| betrivers | +130 | -155 |
| caesars | +118 | -148 |
| draftkings | +123 | -149 |
| espnbet | +118 | -148 |
| fanduel | +112 | -132 |
| pinnacle | +321 | -427 |
Houston Astros vs Cleveland Guardians: recap & odds
Houston Astros lost to Cleveland Guardians 5–8 on Tuesday, April 21, 2026. Closing moneyline prices ranged across 8 sportsbooks: Houston Astros from +112 to +321.
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