MLB · Wednesday, September 16, 2026
Chicago White Sox vs Cleveland Guardians — Prediction, Projected Score & Odds
Chicago White Sox schedule & results·Cleveland Guardians schedule & results
First pitch 13:10 (local)
EdgeBets Model Projection
Chicago White Sox
4.0
Projected Total
8.6
Cleveland Guardians
4.6
Our simulation projects a close matchup with no strong lean either way — the projected total (8.6) is the more useful read here.
Our model's simulation, shown for informational purposes — not betting advice, and not a claim to beat the market.
Moneyline Odds by Sportsbook
as of Sep 16, 9:00 AM ET| Book | Chicago White Sox | Cleveland Guardians |
|---|---|---|
| betmgm | +144 | -172 |
| betrivers | +145 | -180 |
| caesars | +143 | -175 |
| draftkings | +149 | -181 |
| fanduel | +135 | -161 |
| pinnacle | +157 | -175 |
Best available price: Chicago White Sox +157 at Pinnacle. Cleveland Guardians -161 at FanDuel.
Chicago White Sox vs Cleveland Guardians: the matchup & where to bet it
EdgeBets' model projects Chicago White Sox vs Cleveland Guardians at about 4.0–4.6, a total near 8.6 runs. The Chicago White Sox moneyline ranges from +135 to +157 across 6 books, a 22-point spread — line-shopping meaningfully changes the payout here. Right now the best prices are +157 (pinnacle) on Chicago White Sox and -161 (fanduel) on Cleveland Guardians.
EdgeBets does not claim to beat the closing line or guarantee outcomes. Projections are informational. 19+. Please bet responsibly.